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Panagia Episkopi is an 11th-century Byzantine church in the village of Mesa Gonia, one of the most important medieval religious monuments in the Cyclades. Built by the Byzantine Emperor Alexios I Komnenos, it features remarkable marble iconostasis elements and a miraculous icon of the Virgin Mary.
Built around 1100 CE by order of Emperor Alexios I Komnenos as the seat of the Orthodox Bishop of Santorini. The church was later modified by the Franks who added Gothic architectural elements after the Fourth Crusade (1204). It survived the 1956 earthquake with structural damage and was painstakingly restored over several decades.