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4 neighborhoods selected in this guide.

Porta Nuova and the adjacent Isola neighborhood represent Milan's dramatic transformation into a contemporary European capital, with futuristic skyscrapers rising above a formerly industrial railway district.

The Navigli district is Milan's canal neighborhood, centered on the Naviglio Grande and Naviglio Pavese, the last visible remnants of a once-extensive network of waterways designed by Leonardo da Vinci.
Brera is Milan's most atmospheric neighborhood, a labyrinth of cobblestoned streets lined with independent galleries, antique shops, artisan workshops, and sidewalk cafes radiating from the Pinacoteca di Brera.

The Ticinese quarter is Milan's most youthful and alternative neighborhood, stretching from the Roman columns of San Lorenzo along Corso di Porta Ticinese to the canals of the Navigli.