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4 neighborhoods selected in this guide.

Petite France is Strasbourg's most enchanting quarter — a labyrinth of half-timbered houses, narrow cobblestone lanes, and flower-decked bridges spanning the channels of the River Ill. This UNESCO World Heritage district looks like a living postcard of medieval Alsace.

The Grande Île is the historic island at the center of Strasbourg, encircled by the River Ill. It was inscribed as a UNESCO World Heritage site in 1988 — the first time an entire city center received this distinction — and concentrates the cathedral, Petite France, and the city's finest medieval, Renaissance, and Baroque architecture.

The Neustadt (New City) is a remarkable German Imperial quarter built between 1871 and 1918, when Strasbourg was the capital of the German Reichsland Elsaß-Lothringen. Its grand boulevards, monumental public buildings, and Jugendstil (Art Nouveau) residences were inscribed as a UNESCO World Heritage site extension in 2017.

Krutenau is Strasbourg's liveliest student and bohemian quarter — a maze of narrow streets south of the cathedral filled with independent cafés, ethnic restaurants, vintage shops, and the city's most vibrant nightlife scene.